Cargando…

DLiP-PPI library: An integrated chemical database of small-to-medium-sized molecules targeting protein–protein interactions

Protein–protein interactions (PPIs) are recognized as important targets in drug discovery. The characteristics of molecules that inhibit PPIs differ from those of small-molecule compounds. We developed a novel chemical library database system (DLiP) to design PPI inhibitors. A total of 32,647 PPI-re...

Descripción completa

Detalles Bibliográficos
Autores principales: Ikeda, Kazuyoshi, Maezawa, Yuta, Yonezawa, Tomoki, Shimizu, Yugo, Tashiro, Toshiyuki, Kanai, Satoru, Sugaya, Nobuyoshi, Masuda, Yoshiaki, Inoue, Naoko, Niimi, Tatsuya, Masuya, Keiichi, Mizuguchi, Kenji, Furuya, Toshio, Osawa, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868583/
https://www.ncbi.nlm.nih.gov/pubmed/36700083
http://dx.doi.org/10.3389/fchem.2022.1090643