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Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
T-cell receptor-mimetic antibodies (TCRms) targeting disease-associated peptides presented by Major Histocompatibility Complexes (pMHCs) are set to become a major new drug modality. However, we lack a general understanding of how TCRms engage pMHC targets, which is crucial for predicting their speci...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868621/ https://www.ncbi.nlm.nih.gov/pubmed/36700202 http://dx.doi.org/10.3389/fimmu.2022.1080596 |