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Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways
Osteoarthritis (OA) is a trauma-/age-related degenerative disease characterized by chronic inflammation as one of its pathogenic mechanisms. Mulberroside A (MA), a natural bioactive withanolide, demonstrates anti-inflammatory properties in various diseases; however, little is known about the effect...
Autores principales: | Lu, Rui, Wei, Zhenni, Wang, Zhenggang, Xu, Shimeng, Sun, Kai, Cheng, Peng, Huang, Xiaojian, You, Hongbo, Guo, Fengjing, Liang, Shuang, Chen, An-min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868682/ https://www.ncbi.nlm.nih.gov/pubmed/36698724 http://dx.doi.org/10.1016/j.isci.2023.105936 |
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