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Development of sex- and genotype-specific behavioral phenotypes in a Shank3 mouse model for neurodevelopmental disorders

Individuals with a SHANK3-related neurodevelopmental disorder, also termed Phelan-McDermid syndrome or abbreviated as PMS, exhibit significant global developmental delay, language impairment, and muscular hypotonia. Also common are repetitive behaviors and altered social interactions, in line with a...

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Detalles Bibliográficos
Autores principales: Bauer, Helen Friedericke, Delling, Jan Philipp, Bockmann, Jürgen, Boeckers, Tobias M., Schön, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868822/
https://www.ncbi.nlm.nih.gov/pubmed/36699652
http://dx.doi.org/10.3389/fnbeh.2022.1051175