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Inducible miR-1224 silences cerebrovascular Serpine1 and restores blood flow to the stroke-affected site of the brain

The α-tocotrienol (TCT) form of natural vitamin E is more potent than the better known α-tocopherol against stroke. Angiographic studies of canine stroke have revealed beneficial cerebrovascular effects of TCT. This work seeks to understand the molecular basis of such effect. In mice, TCT supplement...

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Detalles Bibliográficos
Autores principales: Palakurti, Ravichand, Biswas, Nirupam, Roy, Sashwati, Gnyawali, Surya C., Sinha, Mithun, Singh, Kanhaiya, Ghatak, Subhadip, Sen, Chandan K., Khanna, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868883/
https://www.ncbi.nlm.nih.gov/pubmed/36726407
http://dx.doi.org/10.1016/j.omtn.2022.12.019