Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth

Structural alterations of collagen impact signaling that helps control tumor progression and the responses to therapeutic intervention. Integrins represent a class of receptors that include members that mediate collagen signaling. However, a strategy of directly targeting integrins to control tumor...

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Detalles Bibliográficos
Autores principales: Caron, Jennifer M., Han, Xianghua, Lary, Christine W., Sathyanarayana, Pradeep, Remick, Scot C., Ernstoff, Marc S., Herlyn, Meenhard, Brooks, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868893/
https://www.ncbi.nlm.nih.gov/pubmed/36633146
http://dx.doi.org/10.3892/or.2023.8481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868893/
https://www.ncbi.nlm.nih.gov/pubmed/36633146
http://dx.doi.org/10.3892/or.2023.8481

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