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Akkermansia deficiency and mucin depletion are implicated in intestinal barrier dysfunction as earlier event in the development of inflammation in interleukin-10-deficient mice

BACKGROUND: Dysbiosis and mucin depletion are related with intestinal barrier dysfunction and seems to be an early pathophysiological event in inflammatory bowel disease (IBD). The objective of this work is to study these parameters in the natural history of colitis in IL-10 deficient mice (IL-10(−/...

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Detalles Bibliográficos
Autores principales: López-Cauce, Beatriz, Puerto, Marta, García, Juan José, Ponce-Alonso, Manuel, Becerra-Aparicio, Federico, del Campo, Rosa, Peligros, Isabel, Fernández-Aceñero, María J., Gómez-Navarro, Yésica, Lara, José M., Miranda-Bautista, José, Marín-Jiménez, Ignacio, Bañares, Rafael, Menchén, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869054/
https://www.ncbi.nlm.nih.gov/pubmed/36699599
http://dx.doi.org/10.3389/fmicb.2022.1083884