Very large hidden genetic diversity in one single tumor: evidence for tumors-in-tumor

Despite the concern of within-tumor genetic diversity, this diversity is in fact limited by the kinship among cells in the tumor. Indeed, genomic studies have amply supported the ‘Nowell dogma’ whereby cells of the same tumor descend from a single progenitor cell. In parallel, genomic data also sugg...

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Detalles Bibliográficos
Autores principales: Chen, Bingjie, Wu, Xianrui, Ruan, Yongsen, Zhang, Yulin, Cai, Qichun, Zapata, Luis, Wu, Chung-I, Lan, Ping, Wen, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869076/
https://www.ncbi.nlm.nih.gov/pubmed/36694802
http://dx.doi.org/10.1093/nsr/nwac250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869076/
https://www.ncbi.nlm.nih.gov/pubmed/36694802
http://dx.doi.org/10.1093/nsr/nwac250

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