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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature
Activation of cellular hypoxia pathways, orchestrated by HIF (hypoxia-inducible factor) transcription factors, is a common feature of multiple tumor types, resulting from microenvironment factors and oncogenic mutation. Although they help drive many of the “hallmarks” of cancer and are associated wi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869179/ https://www.ncbi.nlm.nih.gov/pubmed/36384128 http://dx.doi.org/10.1016/j.celrep.2022.111652 |