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The expression pattern of GDF15 in human brain changes during aging and in Alzheimer’s disease

INTRODUCTION: Growth Differentiation Factor 15 (GDF15) is a mitochondrial-stress-responsive molecule whose expression strongly increases with aging and age-related diseases. However, its role in neurodegenerative diseases, including Alzheimer’s disease (AD), is still debated. METHODS: We have charac...

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Detalles Bibliográficos
Autores principales: Chiariello, Antonio, Valente, Sabrina, Pasquinelli, Gianandrea, Baracca, Alessandra, Sgarbi, Gianluca, Solaini, Giancarlo, Medici, Valentina, Fantini, Valentina, Poloni, Tino Emanuele, Tognocchi, Monica, Arcaro, Marina, Galimberti, Daniela, Franceschi, Claudio, Capri, Miriam, Salvioli, Stefano, Conte, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869280/
https://www.ncbi.nlm.nih.gov/pubmed/36698863
http://dx.doi.org/10.3389/fnagi.2022.1058665