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mSigHdp: hierarchical Dirichlet process mixture modeling for mutational signature discovery
Mutational signatures are characteristic patterns of mutations caused by endogenous or exogenous mutational processes. These signatures can be discovered by analyzing mutations in large sets of samples—usually somatic mutations in tumor samples. Most programs for discovering mutational signatures ar...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869330/ https://www.ncbi.nlm.nih.gov/pubmed/36694663 http://dx.doi.org/10.1093/nargab/lqad005 |