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mSigHdp: hierarchical Dirichlet process mixture modeling for mutational signature discovery

Mutational signatures are characteristic patterns of mutations caused by endogenous or exogenous mutational processes. These signatures can be discovered by analyzing mutations in large sets of samples—usually somatic mutations in tumor samples. Most programs for discovering mutational signatures ar...

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Detalles Bibliográficos
Autores principales: Liu, Mo, Wu, Yang, Jiang, Nanhai, Boot, Arnoud, Rozen, Steven G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869330/
https://www.ncbi.nlm.nih.gov/pubmed/36694663
http://dx.doi.org/10.1093/nargab/lqad005