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Impact of Rabeprazole on APO-Dabigatran Exposure in Healthy Volunteers

BACKGROUND: Dabigatran is effective and safe for stroke prevention in patients with atrial fibrillation and for venous thromboembolism prevention and treatment. In Canada, APO-dabigatran, a generic formulation, has been approved based on a bioequivalence study, but its bioavailability in settings of...

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Detalles Bibliográficos
Autores principales: Chan, Noel, Wheeler, Matt, Bhagirath, Vinai, Bosch, Jacqueline, Heinrich-Nols, Jutta, Sloane, Debbie, van Ryn, Joanne, Jefferies, Linda, Wilkinson, Jacqueline, Yi, Qilong, Eikelboom, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869351/
https://www.ncbi.nlm.nih.gov/pubmed/36700178
http://dx.doi.org/10.1016/j.cjco.2022.09.006