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CCL3 secreted by hepatocytes promotes the metastasis of intrahepatic cholangiocarcinoma by VIRMA-mediated N6-methyladenosine (m(6)A) modification

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is a malignant disease characterized by onset occult, rapid progression, high relapse rate, and high mortality. However, data on how the tumor microenvironment (TME) regulates ICC metastasis at the transcriptomic level remains unclear. This study aim...

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Detalles Bibliográficos
Autores principales: Zhou, Shurui, Yang, Kege, Chen, Shaojie, Lian, Guoda, Huang, Yuzhou, Yao, Hanming, Zhao, Yue, Huang, Kaihong, Yin, Dong, Lin, Haoming, Li, Yaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869516/
https://www.ncbi.nlm.nih.gov/pubmed/36691046
http://dx.doi.org/10.1186/s12967-023-03897-y