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Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization

BACKGROUND: We have investigated the efficacy of a new strategy to limit pathological retinal neovascularization (RNV) during ischemic retinopathy by targeting the cholesterol metabolizing enzyme acyl-coenzyme A: cholesterol transferase 1 (ACAT1). Dyslipidemia and cholesterol accumulation have been...

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Detalles Bibliográficos
Autores principales: Zaidi, Syed A. H., Lemtalsi, Tahira, Xu, Zhimin, Santana, Isabella, Sandow, Porsche, Labazi, Leila, Caldwell, Robert W., Caldwell, Ruth B., Rojas, Modesto A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869542/
https://www.ncbi.nlm.nih.gov/pubmed/36691048
http://dx.doi.org/10.1186/s12974-023-02700-5