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Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization

BACKGROUND: We have investigated the efficacy of a new strategy to limit pathological retinal neovascularization (RNV) during ischemic retinopathy by targeting the cholesterol metabolizing enzyme acyl-coenzyme A: cholesterol transferase 1 (ACAT1). Dyslipidemia and cholesterol accumulation have been...

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Detalles Bibliográficos
Autores principales:	Zaidi, Syed A. H., Lemtalsi, Tahira, Xu, Zhimin, Santana, Isabella, Sandow, Porsche, Labazi, Leila, Caldwell, Robert W., Caldwell, Ruth B., Rojas, Modesto A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869542/ https://www.ncbi.nlm.nih.gov/pubmed/36691048 http://dx.doi.org/10.1186/s12974-023-02700-5

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