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Metabolic profiling reveals metabolic features of consolidation therapy in pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) and its treatment continue to pose substantial risks. To understand ALL more deeply, the metabolome in fasting plasma of 27 ALL patients before and after high-dose methotrexate therapies (consolidation therapy) including methotrexate and 6-mercaptopurine (6-MP) was...

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Detalles Bibliográficos
Autores principales: Fu, Jinqiu, Zhang, Aijun, Liu, Qinqin, Li, Dong, Wang, Xiaoming, Si, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869545/
https://www.ncbi.nlm.nih.gov/pubmed/36691092
http://dx.doi.org/10.1186/s40170-023-00302-6