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The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice
BACKGROUND: Previous studies have shown that depression is often accompanied by an increase in mtDNA copy number and a decrease in ATP levels; however, the exact regulatory mechanisms remain unclear. METHODS: In the present study, Western blot, cell knockdown, immunofluorescence, immunoprecipitation...
Autores principales: | Wang, Bin, Shi, Haixia, Yang, Bo, Miao, Zhigang, Sun, Miao, Yang, Hao, Xu, Xingshun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869592/ https://www.ncbi.nlm.nih.gov/pubmed/36691038 http://dx.doi.org/10.1186/s12964-022-01034-8 |
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