Mesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin

BACKGROUND: Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, PM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supply of stimulat...

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Detalles Bibliográficos
Autores principales: Ries, Alexander, Flehberger, Daniela, Slany, Astrid, Pirker, Christine, Mader, Johanna C., Mohr, Thomas, Schelch, Karin, Sinn, Katharina, Mosleh, Berta, Hoda, Mir Alireza, Dome, Balazs, Dolznig, Helmut, Krupitza, Georg, Müllauer, Leonhard, Gerner, Christopher, Berger, Walter, Grusch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869633/
https://www.ncbi.nlm.nih.gov/pubmed/36683050
http://dx.doi.org/10.1186/s13046-022-02582-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869633/
https://www.ncbi.nlm.nih.gov/pubmed/36683050
http://dx.doi.org/10.1186/s13046-022-02582-0

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