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Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol-induced cell death and heart failure
CXCR4 is a seven-transmembrane-spanning Gi-coupled receptor for the SDF-1 chemokine and plays a critical role in cardiovascular development and post-injury repair. However, the specific role of CXCR4 in cardiomyocytes is incompletely understood. It was hypothesized that CXCR4 activation in cardiomyo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869727/ https://www.ncbi.nlm.nih.gov/pubmed/36579657 http://dx.doi.org/10.3892/ijmm.2022.5216 |