Antitumor activities of a defucosylated anti-EpCAM monoclonal antibody in colorectal carcinoma xenograft models

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein, which is highly expressed on tumor cells. As EpCAM plays a crucial role in cell adhesion, survival, proliferation, stemness, and tumorigenesis, it has been considered as a promising target for tumor diagnosis and thera...

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Detalles Bibliográficos
Autores principales: Li, Guanjie, Suzuki, Hiroyuki, Ohishi, Tomokazu, Asano, Teizo, Tanaka, Tomohiro, Yanaka, Miyuki, Nakamura, Takuro, yoshikawa, Takeo, Kawada, Manabu, Kaneko, Mika K., Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869728/
https://www.ncbi.nlm.nih.gov/pubmed/36660940
http://dx.doi.org/10.3892/ijmm.2023.5221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869728/
https://www.ncbi.nlm.nih.gov/pubmed/36660940
http://dx.doi.org/10.3892/ijmm.2023.5221

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