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Overexpression of miR-148a-3p inhibits extracellular matrix degradation and alleviates IL-1β-induced intervertebral disc degeneration

OBJECTIVE(S): Recently, studies on microRNAs (miRNAs) and their targets and related genes have provided new therapeutic opportunities for controlling intervertebral disc degeneration (IDD). We aimed to investigate the effects of miR-148a-3p overexpression on IDD progression. MATERIALS AND METHODS: T...

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Detalles Bibliográficos
Autores principales: Lai, Hehuan, Fan, Jialin, Zhang, Yejin, Pan, Bin, Pan, Wenzheng, Fang, Jiawei, Ni, Kainan, Chen, Zhenzhong, Liu, Shijie, Lou, Chao, He, Dengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869879/
https://www.ncbi.nlm.nih.gov/pubmed/36742139
http://dx.doi.org/10.22038/IJBMS.2022.64645.14228