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The protective effect of Apelin-13 against cardiac hypertrophy through activating the PI3K-AKT-mTOR signaling pathway

OBJECTIVE(S): To determine the protective effect of Apelin-13 on cardiac hypertrophy through activating the PI3K-AKT-mTOR signaling pathway. MATERIALS AND METHODS: The phenylephrine-induced cardiomyocyte hypertrophy model was established in H9C2 cells in vitro. Electroporation transfection technolog...

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Detalles Bibliográficos
Autores principales: Peng, Yu, Jingming, Ruan, Shaowen, Chen, Feng, Huang, Pengli, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869881/
https://www.ncbi.nlm.nih.gov/pubmed/36742144
http://dx.doi.org/10.22038/IJBMS.2022.65160.14356