FMS-Like Tyrosine Kinase 3 Inhibitors in the Treatment of Acute Myeloid Leukemia: An Update on the Emerging Evidence and Safety Profile

FMS-like tyrosine kinase 3 (FLT3) is one of the most frequently mutated genes in acute myeloid leukemia (AML). Approximately 30% of the adult cases harbor an internal tandem duplication (FLT3-ITD) and 5–10% a tyrosine kinase domain (TKD) amino acid substitution (FLT3-TKD). The treatment paradigm of...

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Detalles Bibliográficos
Autores principales: Garciaz, Sylvain, Hospital, Marie-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869913/
https://www.ncbi.nlm.nih.gov/pubmed/36698434
http://dx.doi.org/10.2147/OTT.S236740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869913/
https://www.ncbi.nlm.nih.gov/pubmed/36698434
http://dx.doi.org/10.2147/OTT.S236740

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