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Deficiency of CFB attenuates renal tubulointerstitial damage by inhibiting ceramide synthesis in diabetic kidney disease

Accumulating evidence suggests the pathogenic role of immunity and metabolism in diabetic kidney disease (DKD). Herein, we aimed to investigate the effect of complement factor B (CFB) on lipid metabolism in the development of DKD. We found that in patients with diabetic nephropathy, the staining of...

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Detalles Bibliográficos
Autores principales: Sun, Zi-jun, Chang, Dong-yuan, Chen, Min, Zhao, Ming-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869976/
https://www.ncbi.nlm.nih.gov/pubmed/36546481
http://dx.doi.org/10.1172/jci.insight.156748