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Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation

Cisplatin-induced ototoxicity is caused by reactive oxygen species. It has been recognized that estradiol (E2) regulates redox balance. However, little is known about the protective mechanisms of E2 against cisplatin-induced ototoxicity. In this study, we investigated the effect of E2 on nuclear fac...

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Detalles Bibliográficos
Autores principales: Adachi, Masahiro, Yanagizono, Kota, Okano, Yasuhito, Koizumi, Hitoshi, Uemaetomari, Isao, Tabuchi, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869986/
https://www.ncbi.nlm.nih.gov/pubmed/36661237
http://dx.doi.org/10.1080/13510002.2022.2161224