Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P-glycoprotein expression levels

A series of 1H-benzo[f]chromene moieties (4a–z) were synthesised under Ultrasonic irradiation and confirmed with spectral analyses. Derivative 4i solely possessed an X-ray single crystal. The anti-proliferative efficacy of the desired molecules has been explored against three cancer cells: MCF-7, HC...

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Detalles Bibliográficos
Autores principales: Al‑Harbi, Lali M., Al-Harbi, Eman A., Okasha, Rawda M., El-Eisawy, R. A., El-Nassag, Mohammed A. A., Mohamed, Hany M., Fouda, Ahmed M., Elhenawy, Ahmed A., Mora, Ahmed, El-Agrody, Ahmed M., El-Mawgoud, Heba K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869995/
https://www.ncbi.nlm.nih.gov/pubmed/36662632
http://dx.doi.org/10.1080/14756366.2022.2155814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869995/
https://www.ncbi.nlm.nih.gov/pubmed/36662632
http://dx.doi.org/10.1080/14756366.2022.2155814

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