Novel insights into the synergistic effects of selenium nanoparticles and metformin treatment of letrozole - induced polycystic ovarian syndrome: targeting PI3K/Akt signalling pathway, redox status and mitochondrial dysfunction in ovarian tissue

PURPOSE: Polycystic ovary syndrome (PCOS) has a series of reproductive and metabolic consequences. Although the link between PCOS, IR, and obesity, their impact on the pathogenesis of PCOS has yet to be determined. Dysfunction of PI3K/AKT pathway has been reported as the main cause of IR in PCOS. Th...

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Detalles Bibliográficos
Autores principales: Rabah, Hanem M., Mohamed, Darin A., Mariah, Reham A., Abd El-Khalik, Sarah R., Khattab, Haidy A., AbuoHashish, Norhan A., Abdelsattar, Amal M., Raslan, Mohamed A., Farghal, Eman E., Eltokhy, Amira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870018/
https://www.ncbi.nlm.nih.gov/pubmed/36661246
http://dx.doi.org/10.1080/13510002.2022.2160569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870018/
https://www.ncbi.nlm.nih.gov/pubmed/36661246
http://dx.doi.org/10.1080/13510002.2022.2160569

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