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Structure–activity relationship of a peptide permeation enhancer

The pentapeptide L-R5 has previously been shown to transiently increase the permeability of nasal epithelial cell layers in vitro, allowing paracellular transport of molecules of up to 4 kDa. Protein kinase C zeta (PKC ζ), a member of a family of serine/threonine kinases was shown to be involved in...

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Detalles Bibliográficos
Autores principales: Brunner, Joël, Borchard, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870020/
https://www.ncbi.nlm.nih.gov/pubmed/35369830
http://dx.doi.org/10.1080/21688370.2022.2060692