Skeletal muscle mitochondrial inertia is associated with carnitine acetyltransferase activity and physical function in humans

BACKGROUND: At the onset of exercise, the speed at which phosphocreatine (PCr) decreases toward a new steady state (PCr on-kinetics) reflects the readiness to activate mitochondrial ATP synthesis, which is secondary to Acetyl-CoA availability in skeletal muscle. We hypothesized that PCr on-kinetics...

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Detalles Bibliográficos
Autores principales: Mancilla, Rodrigo F., Lindeboom, Lucas, Grevendonk, Lotte, Hoeks, Joris, Koves, Tim R., Muoio, Deborah M., Schrauwen, Patrick, Schrauwen-Hinderling, Vera, Hesselink, Matthijs K.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870054/
https://www.ncbi.nlm.nih.gov/pubmed/36413408
http://dx.doi.org/10.1172/jci.insight.163855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870054/
https://www.ncbi.nlm.nih.gov/pubmed/36413408
http://dx.doi.org/10.1172/jci.insight.163855

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