Iron therapy mitigates chronic kidney disease progression by regulating intracellular iron status of kidney macrophages

Systemic iron metabolism is disrupted in chronic kidney disease (CKD). However, little is known about local kidney iron homeostasis and its role in kidney fibrosis. Kidney-specific effects of iron therapy in CKD also remain elusive. Here, we elucidate the role of macrophage iron status in kidney fib...

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Detalles Bibliográficos
Autores principales: Patino, Edwin, Bhatia, Divya, Vance, Steven Z., Antypiuk, Ada, Uni, Rie, Campbell, Chantalle, Castillo, Carlo G., Jaouni, Shahd, Vinchi, Francesca, Choi, Mary E., Akchurin, Oleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870080/
https://www.ncbi.nlm.nih.gov/pubmed/36394951
http://dx.doi.org/10.1172/jci.insight.159235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870080/
https://www.ncbi.nlm.nih.gov/pubmed/36394951
http://dx.doi.org/10.1172/jci.insight.159235

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