CCN2 deficiency in smooth muscle cells triggers cell reprogramming and aggravates aneurysm development

Vascular smooth muscle cell (SMC) phenotypic switching is widely recognized as a key mechanism responsible for the pathogenesis of several aortic diseases, such as aortic aneurysm. Cellular communication network factor 2 (CCN2), often upregulated in human pathologies and animal disease models, exert...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Liu, Xuesong, Xu, Qian, Xu, Wei, Zhou, Xianming, Leask, Andrew, Lin, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870081/
https://www.ncbi.nlm.nih.gov/pubmed/36625347
http://dx.doi.org/10.1172/jci.insight.162987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870081/
https://www.ncbi.nlm.nih.gov/pubmed/36625347
http://dx.doi.org/10.1172/jci.insight.162987

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