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CCN2 deficiency in smooth muscle cells triggers cell reprogramming and aggravates aneurysm development

Vascular smooth muscle cell (SMC) phenotypic switching is widely recognized as a key mechanism responsible for the pathogenesis of several aortic diseases, such as aortic aneurysm. Cellular communication network factor 2 (CCN2), often upregulated in human pathologies and animal disease models, exert...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Liu, Xuesong, Xu, Qian, Xu, Wei, Zhou, Xianming, Leask, Andrew, Lin, Zhiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870081/ https://www.ncbi.nlm.nih.gov/pubmed/36625347 http://dx.doi.org/10.1172/jci.insight.162987

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