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Mitochondrial fission and bioenergetics mediate human lung fibroblast durotaxis

Pulmonary fibrosis is characterized by stiffening of the extracellular matrix. Fibroblasts migrate in the direction of greater stiffness, a phenomenon termed durotaxis. The mechanically guided fibroblast migration could be a crucial step in the progression of lung fibrosis. In this study, we found p...

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Detalles Bibliográficos
Autores principales: Guo, Ting, Jiang, Chun-sun, Yang, Shan-Zhong, Zhu, Yi, He, Chao, Carter, A. Brent, Antony, Veena B., Peng, Hong, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870082/
https://www.ncbi.nlm.nih.gov/pubmed/36422990
http://dx.doi.org/10.1172/jci.insight.157348