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Multicytokine-producing CD4(+) T cells characterize the livers of patients with NASH

A role of CD4(+) T cells during the progression from nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH) has been suggested, but which polarization state of these cells characterizes this progression and the development of fibrosis remain unclear. In addition, a gut-liver...

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Detalles Bibliográficos
Autores principales: Woestemeier, Anna, Scognamiglio, Pasquale, Zhao, Yu, Wagner, Jonas, Muscate, Franziska, Casar, Christian, Siracusa, Francesco, Cortesi, Filippo, Agalioti, Theodora, Müller, Simone, Sagebiel, Adrian, Konczalla, Leonie, Wahib, Ramez, Karstens, Karl-Frederick, Giannou, Anastasios D., Duprée, Anna, Wolter, Stefan, Wong, Milagros N., Mühlig, Anne K., Bielecka, Agata A., Bansal, Vikas, Zhang, Tianran, Mann, Oliver, Puelles, Victor G., Huber, Tobias B., Lohse, Ansgar W., Izbicki, Jakob R., Palm, Noah W., Bonn, Stefan, Huber, Samuel, Gagliani, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870087/
https://www.ncbi.nlm.nih.gov/pubmed/36625344
http://dx.doi.org/10.1172/jci.insight.153831