HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

Carbohydrate response element–binding protein (ChREBP) is a carbohydrate-sensing transcription factor that regulates both adaptive and maladaptive genomic responses in coordination of systemic fuel homeostasis. Genetic variants in the ChREBP locus associate with diverse metabolic traits in humans, i...

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Detalles Bibliográficos
Autores principales: Sargsyan, Ashot, Doridot, Ludivine, Hannou, Sarah A., Tong, Wenxin, Srinivasan, Harini, Ivison, Rachael, Monn, Ruby, Kou, Henry H., Haldeman, Jonathan M., Arlotto, Michelle, White, Phillip J., Grimsrud, Paul A., Astapova, Inna, Tsai, Linus T., Herman, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870088/
https://www.ncbi.nlm.nih.gov/pubmed/36413406
http://dx.doi.org/10.1172/jci.insight.153740