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HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis
Carbohydrate response element–binding protein (ChREBP) is a carbohydrate-sensing transcription factor that regulates both adaptive and maladaptive genomic responses in coordination of systemic fuel homeostasis. Genetic variants in the ChREBP locus associate with diverse metabolic traits in humans, i...
Autores principales: | Sargsyan, Ashot, Doridot, Ludivine, Hannou, Sarah A., Tong, Wenxin, Srinivasan, Harini, Ivison, Rachael, Monn, Ruby, Kou, Henry H., Haldeman, Jonathan M., Arlotto, Michelle, White, Phillip J., Grimsrud, Paul A., Astapova, Inna, Tsai, Linus T., Herman, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870088/ https://www.ncbi.nlm.nih.gov/pubmed/36413406 http://dx.doi.org/10.1172/jci.insight.153740 |
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