Ubiquitination of stalled ribosomes enables mRNA decay via HBS-1 and NONU-1 in vivo

As ribosomes translate the genetic code, they can encounter a variety of obstacles that hinder their progress. If ribosomes stall for prolonged times, cells suffer due to the loss of translating ribosomes and the accumulation of aberrant protein products. Thus to protect cells, stalled ribosomes exp...

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Detalles Bibliográficos
Autores principales: Monem, Parissa C., Vidyasagar, Nitin, Piatt, Audrey L., Sehgal, Enisha, Arribere, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870110/
https://www.ncbi.nlm.nih.gov/pubmed/36626369
http://dx.doi.org/10.1371/journal.pgen.1010577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870110/
https://www.ncbi.nlm.nih.gov/pubmed/36626369
http://dx.doi.org/10.1371/journal.pgen.1010577

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