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Ubiquitination of stalled ribosomes enables mRNA decay via HBS-1 and NONU-1 in vivo
As ribosomes translate the genetic code, they can encounter a variety of obstacles that hinder their progress. If ribosomes stall for prolonged times, cells suffer due to the loss of translating ribosomes and the accumulation of aberrant protein products. Thus to protect cells, stalled ribosomes exp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870110/ https://www.ncbi.nlm.nih.gov/pubmed/36626369 http://dx.doi.org/10.1371/journal.pgen.1010577 |