The effect of in vitro consecutive passages and culture medium on the genetic variations in BCG Pasteur 1173P2 vaccine

Since the introduction of the Bacillus Calmette–Guérin (BCG) vaccine, the genomes of vaccine strains have undergone variations due to repeated passages in different laboratories and vaccine production facilities. Genetic variations have been considered as one of the effective factors in the BCG vari...

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Detalles Bibliográficos
Autores principales: Asadian, Mahla, Hassanzadeh, Seyed Mehdi, Safarchi, Azadeh, Douraghi, Masoumeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870133/
https://www.ncbi.nlm.nih.gov/pubmed/36689397
http://dx.doi.org/10.1371/journal.pone.0280294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870133/
https://www.ncbi.nlm.nih.gov/pubmed/36689397
http://dx.doi.org/10.1371/journal.pone.0280294

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