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The association between a genetic variant in the SULF2 gene, metabolic parameters and vascular disease in patients at high cardiovascular risk

Clearance of triglyceride-rich lipoproteins (TRLs) is mediated by several receptors, including heparan sulfate proteoglycans (HSPGs). Sulfate glucosamine-6-O-endosulfatase-2 is a gene related to the regulation of HSPG. A variant in this gene, rs2281279, has been shown to be associated with triglycer...

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Detalles Bibliográficos
Autores principales: Heidemann, Britt E, Visseren, Frank LJ, van Setten, Jessica, Marais, A David, Koopal, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870215/
https://www.ncbi.nlm.nih.gov/pubmed/36699192
http://dx.doi.org/10.1097/XCE.0000000000000278