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Luteolin-rich fraction from Perilla frutescens seed meal inhibits spike glycoprotein S1 of SARS-CoV-2-induced NLRP3 inflammasome lung cell inflammation via regulation of JAK1/STAT3 pathway: A potential anti-inflammatory compound against inflammation-induced long-COVID

OBJECTIVE: The multi-systemic inflammation as a result of COVID-19 can persevere long after the initial symptoms of the illness have subsided. These effects are referred to as Long-COVID. Our research focused on the contribution of the Spike protein S1 subunit of SARS-CoV-2 (Spike S1) on the lung in...

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Detalles Bibliográficos
Autores principales: Dissook, Sivamoke, Umsumarng, Sonthaya, Mapoung, Sariya, Semmarath, Warathit, Arjsri, Punnida, Srisawad, Kamonwan, Dejkriengkraikul, Pornngarm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870545/
https://www.ncbi.nlm.nih.gov/pubmed/36698809
http://dx.doi.org/10.3389/fmed.2022.1072056