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RIG‐I‐mediated innate immune signaling in tumors reduces the therapeutic effect of oncolytic vesicular stomatitis virus

BACKGROUND: Oncolytic viral therapy is a promising method for tumor treatment. Currently, several oncolytic viruses (OVs) have been used as tumor therapy at different phases of research and clinical trials. OVs not only directly lyse tumor cells due to viral replication but also initiate host antitu...

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Detalles Bibliográficos
Autores principales: Zhang, Pengfei, Han, Xinyu, Tan, Weiqi, Chen, Dahua, Sun, Qinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870728/
https://www.ncbi.nlm.nih.gov/pubmed/36447430
http://dx.doi.org/10.1111/1759-7714.14740