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Catechol-O-methyl transferase suppresses cell invasion and interplays with MET signaling in estrogen dependent breast cancer

Catechol-O-methyl transferase (COMT) is involved in detoxification of catechol estrogens, playing cancer-protective role in cells producing or utilizing estrogen. Moreover, COMT suppressed migration potential of breast cancer (BC) cells. To delineate COMT role in metastasis of estrogen receptor (ER)...

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Detalles Bibliográficos
Autores principales: Janacova, Lucia, Stenckova, Michaela, Lapcik, Petr, Hrachovinova, Sarka, Bouchalova, Pavla, Potesil, David, Hrstka, Roman, Müller, Petr, Bouchal, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870911/
https://www.ncbi.nlm.nih.gov/pubmed/36690660
http://dx.doi.org/10.1038/s41598-023-28078-1