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Influence of variability in the cyclooxygenase pathway on cardiovascular outcomes of nephrosclerosis patients

Nephrosclerosis patients are at an exceptionally high cardiovascular (CV) risk. We aimed to determine whether genetic variability represented by 38 tag-SNPs in genes of the cyclooxygenase pathway (PTGS1, PTGS2, PTGES, PTGES2 and PTGES3) leading to prostaglandin E2 (PGE2) synthesis, modified CV trait...

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Detalles Bibliográficos
Autores principales: González, Luz M., Robles, Nicolás R., Mota-Zamorano, Sonia, Valdivielso, José M., González-Rodríguez, Laura, López-Gómez, Juan, Gervasini, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870986/
https://www.ncbi.nlm.nih.gov/pubmed/36690661
http://dx.doi.org/10.1038/s41598-022-27343-z