Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B

DNA methylation is a repressive epigenetic modification that is essential for development, exemplified by the embryonic and perinatal lethality observed in mice lacking de novo DNA methyltransferases (DNMTs). Here we characterise the role for DNMT3A, 3B and 3L in gene regulation and development of t...

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Detalles Bibliográficos
Autores principales: Andrews, Simon, Krueger, Christel, Mellado-Lopez, Maravillas, Hemberger, Myriam, Dean, Wendy, Perez-Garcia, Vicente, Hanna, Courtney W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870994/
https://www.ncbi.nlm.nih.gov/pubmed/36690623
http://dx.doi.org/10.1038/s41467-023-36019-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870994/
https://www.ncbi.nlm.nih.gov/pubmed/36690623
http://dx.doi.org/10.1038/s41467-023-36019-9

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