Mapping the diffusion pattern of (1)O(2) along DNA duplex by guanine photooxidation with an appended biphenyl photosensitizer

To realize nucleic acid-targeting photodynamic therapy, a photosensitizer should be attached at the optimal position on a complementary oligonucleotide, where a guanine photooxidation is maximized. Here we show the photooxidation of 22 DNA duplexes with varied lengths between a (1)O(2)-generating bi...

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Detalles Bibliográficos
Autores principales: Kanamori, Takashi, Kaneko, Shota, Hamamoto, Koji, Yuasa, Hideya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871026/
https://www.ncbi.nlm.nih.gov/pubmed/36690669
http://dx.doi.org/10.1038/s41598-023-27526-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871026/
https://www.ncbi.nlm.nih.gov/pubmed/36690669
http://dx.doi.org/10.1038/s41598-023-27526-2

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