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Mapping the diffusion pattern of (1)O(2) along DNA duplex by guanine photooxidation with an appended biphenyl photosensitizer
To realize nucleic acid-targeting photodynamic therapy, a photosensitizer should be attached at the optimal position on a complementary oligonucleotide, where a guanine photooxidation is maximized. Here we show the photooxidation of 22 DNA duplexes with varied lengths between a (1)O(2)-generating bi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871026/ https://www.ncbi.nlm.nih.gov/pubmed/36690669 http://dx.doi.org/10.1038/s41598-023-27526-2 |