Hepatic TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis

Tumor necrosis factor receptor superfamily member-12A (TNFRSF12A) plays a critical role in inflammation and cell death. It is expressed in multiple tissues yet extremely low in normal liver. To date, little is known about its role in cholestasis. Therefore, we sought to delineate the role of TNFRSF1...

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Detalles Bibliográficos
Autores principales: Liao, Min, Liao, Junwei, Qu, Jiaquan, Shi, Pan, Cheng, Ying, Pan, Qiong, Zhao, Nan, Zhang, Xiaoxun, Zhang, Liangjun, Tan, Ya, Li, Qiao, Zhu, Jin-Fei, Li, Jianwei, Zhang, Chengcheng, Cai, Shi-Ying, Chai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871041/
https://www.ncbi.nlm.nih.gov/pubmed/36690641
http://dx.doi.org/10.1038/s41420-023-01326-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871041/
https://www.ncbi.nlm.nih.gov/pubmed/36690641
http://dx.doi.org/10.1038/s41420-023-01326-z

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