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Direct structure determination of vemurafenib polymorphism from compact spherulites using 3D electron diffraction

The spherulitic morphology is considered to be the most common morphology of crystalline materials and is particularly apparent in melt-crystallized products. Yet, historically, the polycrystalline nature of spherulites has hindered successful crystal structure determination. Here, we report the dir...

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Detalles Bibliográficos
Autores principales: Li, Shuting, Lightowler, Molly, Ou, Xiao, Huang, Siyong, Jiang, Yifan, Li, Xizhen, Zou, Xiaodong, Xu, Hongyi, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871043/
https://www.ncbi.nlm.nih.gov/pubmed/36697943
http://dx.doi.org/10.1038/s42004-022-00804-2