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Direct structure determination of vemurafenib polymorphism from compact spherulites using 3D electron diffraction
The spherulitic morphology is considered to be the most common morphology of crystalline materials and is particularly apparent in melt-crystallized products. Yet, historically, the polycrystalline nature of spherulites has hindered successful crystal structure determination. Here, we report the dir...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871043/ https://www.ncbi.nlm.nih.gov/pubmed/36697943 http://dx.doi.org/10.1038/s42004-022-00804-2 |